LRWD1 Antikörper

Produktnummer ABIN6568759

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch LRWD1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für LRWD1 Antikörper (ABIN6568759)

Target: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRWD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LRWD1 Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human Lrwd1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LRWD1

Target: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Andere Bezeichnung: Lrwd1

Hintergrund:

Synonyms: 1200011O22Rik,AU042569,AW548074,DKFZp434K1815,Leucine rich repeats and WD repeat domain containing 1,Leucine-rich repeat and WD repeat-containing protein 1,LRWD1,LRWD1,ORC-associated protein,ORCA,Origin recognition complex-associated protein

Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 65kDa

Calculated_MW: 70kDa

Gen-ID: 222229

UniProt: Q9UFC0

Pathways: Chromatin Binding